4-(2-AMINOETHYL)BENZENE-SULFONYL FLUORIDE (AEBSF)
Opis
Application Notes
The lower molecular weight and toxicity of AEBSF relative to PMSF and related organophosphate inhibitors, make this inhibitor well suited for blocking trypsin-like activities in tissue culture media as well as in large scale purification of recombinant proteins , susceptible to proteolysis
Biochemical Physiological Actions
Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions.
Typical Working Concentration: AEBSF has been used in cell culture in concentrations of up to 0.25 mM.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Inhibitor | Serine Protease Inhibitors | Trypsin Inhibitors
Dane techniczne
Opakowanie | 50 mg |