Produkty
Producenci
6-Aminopenicillanic acid
Opis
Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com
6-Aminopenicillanic Acid or (+)-6-Aminopenicillanic Acid (6-APA) is an organic dipeptide and the chemical core or "nucleus" of penicillin antibiotics. It was discovered in 1958 (Beecham Group, UK). It is produced from Penicillin by penicillin amidase. 6-APA, a β-lactam, is used as a starting compound for synthesis of semisynthetic Penicillins and may be substituted at the 6-amino position, resulting in a variety of antibacterial properties. It is a precursor to Ampicillin and Amoxicillin.
Cas Number: 551-16-6
Molecular Formula:
C8H12N2O3S
Molecular Weight: 216.26
Mechanism of Action: 6-Aminopenicillanic Acid interferes with the synthesis of bacterial cell walls of Gram-positive bacteria.
Spectrum: Gram-positive bacteria.
Eukaryotic Cell Culture Applications:
The coating of (+)-6-Aminopenicillanic Acid on silver nanoparticles (6APA-AgNPs), can impart an ability to detect chromium (IV) in human erythrocytes.
Appearance: White or almost white crystalline powder
Source: Penicillium
pH: 3.5 – 4.5
Assay: Not less than 96.0%
Loss on Drying: Not more than 0.20%
Absorbance: 425nm - Less than 0.025; Transmittance: 500nm - Not less than 90.0%
Optical Rotation: +265.0°-+285.0°
Identification: IR, HPLC - Passes test
Impurity Profile: Penicillin G K: Not more than 0.1%
Phenylacetic Acid: Not more than 0.1%
References:
Batchelor FR, Doyle FP, Nayler JH and Rolinson GN (1959) Synthesisi of penicillin: 6-Amnopenicillanic acid in penicillin fermentations. Nature 183(4656):257-258
Parmar A, Kumar H, Marwaha SS and Kennedy JF (2000) Advances in enzymatic transformation of penicillins to 6-Aminopenicillanic acid (6-APA). Biotechnol Advances 18(4):289-301
Dane techniczne
| Opakowanie | 25 g |