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A 39183A

nr kat.: A109-5MG
Opakowanie: 5 mg
Cena brutto: 5 614,95 zł 5614.95
Cena netto: 4 565,00 zł
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Producent: TOKU-E
nr kat.: A109-5MG

Opis

Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com

A 39183A is factor A from the A-39183 antibiotic complex. The A-39183 antibiotic complex was isolated from the aerobic fermentation of Streptomyces (strain NRRL 12049) by Eli Lilly in 1979.  This complex contains closely-related factors A, B, C, D, and E with broad-spectrum activity.  The fractions can be separated by chromatography.  A 39183A is a rare 9,9'-bianthryl antibiotic related to setomimycin and it acts as an ionophore.  Factor A is a major component of the complex (36%), along with Factor B (46%).  Factors C-E are minor, together accounting for ~ 18% of the complex.

A 39183A is soluble in ethanol, methanol, DMF, DMSO, acetone, ethyl acetate, and chloroform.  It is practically insoluble in water.

Cas Number: 79426-51-0

Molecular Formula: C34H30O10

Molecular Weight: 598.6

Mechanism of Action: A 38183A acts as an ionophore, aiding the partitioning of Mg+ and Ca+ ions into organic solvents and transport of ferric ions into mitochondria.

Storage Conditions: -20°C

Spectrum: It has broad-spectrum activity against Gram-positive and Gram-negative bacteria including anaerobic species including penicillin-resistant Staphylococcus and Streptococcus.

Source: Streptomyces strain NRRL 12049

Solubility: Soluble in ethanol, methanol, DMF, DMSO, acetone, ethyl acetate, and chloroform. It is practically insoluble in water.

Purity Level: >95% by HPLC

References: Koch K and Kastner RE (1981) Antibiotics and process for production thereof. US Patent 4283390A

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