Produkty
Producenci
Antimycin
Opis
Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com
Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogues in the antimycin A class, mostly involving variation of the fatty acid ester chain length or adjacent alkyl starting unit. Antimycin A is widely used as a bioprobe of respiration and other applications with over 5,000 literature citations.
Antimycin A is soluble in ethanol, methanol, DMF and DMSO.
Cas Number: 1397-94-0
Molecular Formula: C28H40N2O9 (for A1)
Molecular Weight: 548.6 (for A1)
Mechanism of Action: Antimycin A binds to cytochrome C reductase at the Qi site, inhibiting the oxidation of ubiquinol to ubiquinone.
Storage Conditions: -20°C
Purity Level: >95% by HPLC
References: The isolation and properties of antimycin A. Bryant R. & Dunshee B.R. et al. J. Am. Chem. Soc. 1949, 71, 2436.
Inhibition of electron transport by antimycin A, alkyl hydroxy naphthoquinones and metal coordination compounds. Tappel A.L. Biochem. Pharmacol. 1960, 3, 289.
Biosynthetic pathway for high structural diversity of a common dilactone core in antimycin production. Yan Y. et al. Org. Lett. 2012, 14, 4142.
Dane techniczne
| Opakowanie | 5 mg |