Produkty
Producenci

CHLORAMPHENICOL phytopure™

nr kat.: 0219032180
Opakowanie: 100 g
Cena brutto: do wyceny
ilość szt.

towar niedostępny

dodaj do przechowalni
Producent: MP Biomedicals
nr kat.: 0219032180

Opis


Applications
Chloramphenicol and several analogues inhibited DNA synthesis in Ehrlich Ascites cells under aerobic and anaerobic conditions in the presence and absence of glucose. It is used mainly for opthalmic (eye drops) and veterinary purposes. Used as a seletion agent for transformed cells containing chloramphenicol resistance genes.

Product Description
Chloramphenicol is a synthetic antibiotic, which was first isolated from strains of Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Chloramphenicol inhibits bacterial protein synthesis by blocking the peptidyl transferase step (elongation inhibition). It binds to the 50S ribosomal subunit and prevents attachment of aminoacyl tRNA to the ribosome. It inhibits mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, thus de-repressing rRNA transcription.

Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). It is bacteriostatic. Mode of Resistance: Acetylation by chloramphenicol acetyltransferase.

Typical Working Concentration
5 -20 µg/mL

Soluble in methanol (50 mg/mL - clear, pale yellow solution), butanol, ethyl acetate, acetone, ethanol, propylene glycol; slightly soluble in water, ether; insoluble in benzene, petroleum ether, vegetable oils.

Dane techniczne

Opakowanie 100 g
do góry
Sklep jest w trybie podglądu
Pokaż pełną wersję strony
Sklep internetowy Shoper.pl