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PEPSTATIN A

nr kat.: 0219536825
Opakowanie: 25 mg
Cena brutto: do wyceny
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Producent: MP Biomedicals
nr kat.: 0219536825

Opis

Alternate Names Isovaleryl-L-valyl-L-valyl-[(3S, 4S)-4-amino-3-hydroxy-6- methylheptanoyl]-L- alanyl [3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid]; [1S-[1R*,2R*,4[R*[R*(R*)]]]]-N- (3-methyl-1-oxobutyl)-L-valyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3- methylbutyl] amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl]-L-valinamide; N-isovaleryl-L-valyl-L-valyl-3-hydroxy-6-methyl-g-aminoheptanoyl-L- alanyl-3-hydroxy-6-methyl-g-aminoheptanoic acid
Application Notes Pepstatin A can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes.
Base Catalog Number 195368
Beilstein Registry Number 2201362
Biochemical Physiological Actions Pepstatin A is an inhibitor of acid proteases (aspartyl peptidases). It forms a 1:1 complex with proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B (Aspergillus niger). The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine proteases. Solubilized γ-secretase and retroviral protease are also inhibited by Pepstatin A. It has been used to characterize proteases from several sources.
CAS # 26305-03-3
EC Number 247-600-0
Hazard Statements H317
Molecular Formula C34H63N5O9
Personal Protective Equipment Eyeshields, Gloves,respirator filter
RTECS Number SC6155000
Typical Working Concentration Effective concentration is approximately 1 uM (0.5 to 1.0 ug/mL).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

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Opakowanie 25 mg
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