AZTREONAM

Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia.

Molecular Formula: C₁₃H₁₇N₅O₈S₂

Molecular Weight:  435.4

CAS: 78110-38-0

Synonyms: Azthreonam; Azactam; [2S-[2a, 3b(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4- oxo-1-sulfo-3- azetidinyl)amino]-2-oxoethylidene] amino] oxy]-2-methylpropanoic acid

Physical Description: White crystalline powder

Solubility: Soluble in DMF and DMSO; slightly soluble in ethanol and methanol; practically insoluble in toluene, chloroform andethyl acetate.

Description: The first totally synthetic monocyclic b-lactam antibiotic that displays a high degree of resistance to b-lactamasedegradation.1 High specificity for gram-negative aerobic rods
Aztreonam specifically targets the penicillin binding protein 3 (PBP-3) of Gram-negative bacteria. It is also effective against such Enterobacteriaceae as E. coli, Klebsiella, Proteus, Providencia, Salmonella, Serratia, Shigella,and Yersinia species.

Application Notes
Aztreonam specifically targets the penicillin binding protein 3 (PBP-3) of Gram-negative bacteria. It is also effective against such Enterobacteriaceae as E. coli, Klebsiella, Proteus, Providencia, Salmonella, Serratia, Shigella,and Yersinia species.