siRNA designed and modified for greater specificity

ON‑TARGETplus siRNA reagents reduce off-targets utilizing a patented dual-strand modification, while still providing guaranteed gene silencing of human, mouse and rat gene targets. This unmatched potency and specificity make ON‑TARGETplus siRNA the premium choice for optimal knockdown and reduced off-targets.

Highlights

• We now offer a 2 nmol size when purchasing pre-designed ON‑TARGETplus or siGENOME siRNAs for human, mouse, or rat.
• Off-targets reduced by up to 90% compared to unmodified siRNA.
• Guaranteed silencing by SMARTpool and 3 of 4 individual siRNAs (See Product Formats tab).
• Sequence information provided with siRNA purchase.

Product Formats
SMARTpool:
A mixture of 4 siRNA provided as a single reagent; providing advantages in both potency and specificity. siGENOME and ON‑TARGETplus are guaranteed† to silence by 75% or better.

Set of 4:
A convenient option for purchasing aliquots of all 4 individual siRNAs targeting a single gene. Three of four siGENOME and ON‑TARGETplus siRNAs are guaranteed† to silence by 75% or better.

Set of 4 Upgrade:
Discounted price on the Set of 4 based on a concurrent or prior purchase of the SMARTpool reagent for the same gene.

Individual siRNAs:
Select 1, 2, 3 or 4 individual siRNAs per gene.

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