Formic Acid, LC-MS Grade

Thermo Scientific Formic Acid is high-purity solvent supplied in bottles as a convenient, contamination-free alternative for preparing elution solvents for HPLC separations of protein and peptides.

General properties of formic acid
• Molecular formula: HCOOH (CH₂O₂)
• Molecular weight: 46.02
• Density: 1.22 g/mL
• CAS number: 64-18-6
• Refractive index: 1.3701–1.3721(20°C)
• Flash point: 69°C
• Freezing point: 8°C

Specifications of Thermo Scientific Formic Acid
• Visual: Clear liquid, free of particulate matter
• Identity (IR): Must show only peaks characteristic for the compound
• Purity: > 99%
• Refractive index: 1.3701 to 1.3721 (20°C, 589 nm)

Formic Acid is specially purified and tested to the highest specifications to ensure the integrity of your data, maximize sensitivity in your assay and to prolong the life of your equipment.

Formic acid is a common component of reverse-phase mobile phases that provide protons for LC/MS analysis. The presence of a low concentration of formic acid in the mobile phase is also known to improve the peak shapes of the resulting separation. Unlike trifluoroacetic acid (TFA), formic acid is not an ion-pairing agent and it does not suppress MS ionization of polypeptides when used as a mobile-phase component.