Producenci
Ansatrienin B
Opis
Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com
Ansatrienin B, also known as Mycotrienin II and Antibiotic T 23II, was isolated from a Streptomyces sp.. Closely related to the cytotrienins and trienomycins, it displays potent activity against tumor cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents.
Ansatrienin B is soluble in ethanol, methanol, DMF and DMSO.
Cas Number: 82189-04-6
Molecular Formula: C36H50N2O8
Molecular Weight: 638.8
Storage Conditions: -20°C
Purity Level: >95% by HPLC (< 5% Ansatrienin A)
References: Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. Feuerbach D. et al. , J. Biol. Chem. 1995, 270, 25949.
Potentiation of mitomycin C, 6-mercaptopurine, bleomycin, cis-diamminedichloroplatinum and 5-fluoro-uracil by mycotrienins and mycotrienols. Kuwano M. et al. , Gann. 1983, 74, 759.
Studies on mycotrienin antibiotics, a novel class of ansamycins. II. Structure elucidation and biosynthesis of mycotrienins I and II. Sugita M. et al. , J. Antibiot. 1982, 35, 1467.
Dane techniczne
| Opakowanie | 5 mg |