Produkty
Producenci
Asukamycin
Opis
Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com
Asukamycin is an unusual trienoic acid amide metabolite produced by Streptomyces nodosus, reported by Omura and colleagues at the Kitasato Institute, Japan, in 1976. Asukamycin belongs to the manumycin class that comprises two trienoic acid amides pivoted on a central cyclohexenone ring to give the molecule an unprecedented angular geometry. Asukamycin is active against Gram positive bacteria, tumor cell lines and protozoans, notably coccidia. Asukamycin's cell toxicity is accompanied by activation of Caspases 3 and 8.
Asukamycin is soluble in ethanol, methanol, DMF and DMSO.
Cas Number: 61116-33-4
Molecular Formula: C31H34N2O7
Molecular Weight: 546.6
Storage Conditions: -20°C
Purity Level: >95% by HPLC
References: A new antibiotic, asukamycin, produced by Streptomyces. Omura S. et al. J. Antibiot. 1976, 29, 876.
The manumycin-group metabolites. Sattler I. et al. J. Antibiot. 2000, 53, 221.
Antitumor activity of asukamycin, a secondary metabolite from the actinomycete bacterium Streptomyces nodosus subspecies asukaensis. Shipley P.R. et al. Int. J. Mol. Med. 2009, 24, 711.
Dane techniczne
| Opakowanie | 2.5 mg |