Produkty
Producenci
Bafilomycin A1
Opis
Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com
Bafilomycin A1 is a member of a potent family of macrocyclic lactones with broad spectrum biological activity, including activity against bacteria, yeast, fungi, nematodes, insects and tumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase.
Bafilomycin A1 is soluble in ethanol, methanol, DMF and DMSO. NOTE: forms methyl ketal on long term storage in methanol.
Cas Number: 88899-55-2
Molecular Formula: C35H58O9
Molecular Weight: 622.8
Mechanism of Action: Bafilomycin A1 is an inhibitor of vacuolar-type ATPase.
Storage Conditions: -20°C
Purity Level: >95% by HPLC
References: Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Bowman E.J. et al. Proc Natl Acad Sci USA. 1988, 85, 7972.
Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. Yoshimori T. et al. J Biol Chem. 1991, 266, 17707.
Vacuolar ATPase as a drug discovery target. Niikura K. Drug News Perspect. 2006, 19, 139.
Dane techniczne
| Opakowanie | 1 mg |