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Producenci
Blasticidin A
Opis
Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com
Blasticidin A is a high molecular weight tetramic acid isolated from S. resistomycificus in 1955. It has broad-spectrum antifungal and antibacterial activity. Like many tetramic acids, Blasticidin A is isolated as the stable calcium salt/complex. Blasticidin A and closely related Aflastatin A are specific inhibitors of the production of the aflatoxin produced by the fungus Aspergillus parasiticus.
Blasticidin A is soluble in DMF, DMSO and methanol and is moderately soluble in water and ethanol.
Cas Number: 100513-53-9
Molecular Formula: C58H107NO23
Molecular Weight: 1186.5
Mechanism of Action: Blasticidin A inhibits aflatoxin production by Aspergillus parasiticus. It also decreases ribosomal protein levels and inhibits protein synthesis in S. cerevisiae.
Storage Conditions: -20°C
Microbiology Applications: Blasticidin A has antifungal and antibacterial activity. It inhibits aflatoxin production in Aspergillus parasiticus without affecting fungal growth.
Solubility: soluble in DMF, DMSO and methanol and is moderately soluble in water and ethanol.
Purity Level: >98% by HPLC
References: Fukunaga K et al (1955) Blasticidin, a new anti-phytopathogenic fungal substance. Part I. Bull. Agr. Chem. Soc. Jpn. 19(3): 181-188
Sakuda S et al (2000) Blasticidin A as an inhibitor of aflatoxin production by Aspergillus parasiticus. J. Antibiot. (Tokyo) 53 (11): 1265-1271 PMID 11213287
Yoshinari T et al (2010) Inhibitory activity of Blasticidin A, a strong aflatoxin production inhibitor, on protein synthesis of yeast: Selective inhibition of aflatoxin production by protein synthesis inhibitors J. Antibiot. (Tokyo) 63(6): 309-314 PMID 20414321
Dane techniczne
| Opakowanie | 1 mg |