Produkty
Producenci
Bafilomycin C1
Opis
Produkt przeznaczony wyłącznie do badań. Nie nadaje się do spożycia. Więcej informacji na stronie producenta www.toku-e.com
Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.
Bafilomycin C1 is soluble ethanol, methanol, DMF and DMSO.
Cas Number: 88979-61-7
Molecular Formula: C39H60O12
Molecular Weight: 734.9
Mechanism of Action: Bafilomycin C1 is an inhibitor of vacuolar-type ATPase.
Storage Conditions: -20°C
Purity Level: >95% by HPLC
References: Bafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic Nematodes. Lacey E. et al. Int. J. Parasitol. 1995, 25, 349.
Purification of Vacuolar ATPase with Bafilomycin C1 Affinity Chromatography. Rautiala T.J. et al. Biochem. Biophys. Res. Comm. 1993, 194, 50.
Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis. Xu J. et al. Histol. Histopathol. 2007, 22, 443.
Dane techniczne
| Opakowanie | 5 mg |